Meet Inspiring Speakers and Experts at our 3000+ Global Conference Series Events with over 1000+ Conferences, 1000+ Symposiums
and 1000+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business.

Explore and learn more about Conference Series : World's leading Event Organizer

Back

Anka G Ehrhardt

Bristol-Myers Squibb Co., USA

Title: Receptor occupancy in flow cytometry: A key PK/PD option in biologics clinical studies

Biography

Biography: Anka G Ehrhardt

Abstract

Receptor occupancy assays are a key method in dose escalation studies to understand the amount of drug required to cover the available receptors during patient dosing, as well as to deliver PK data for PK/PD work. For many biologics, flow cytometry assays utilizing peripheral blood are well suited for receptor occupancy studies, and are used often in the clinic. This presentation will summarize some of the common considerations and different versions of RO assays in the context of clinical studies.