Biosimilars Approval to Biogenerics in Clinical Practice

Biological medicines are much more structurally complex and extremely sensitive to manufacturing conditions and therefore more difficult to characterize and produce than small molecule drugs. Even minor changes in manufacturing may lead to significant variations of the cellular systems used for biological production, as well as to differences in the structure, stability, or other quality aspects of the end product, all of which have the potential to affect tolerability and/or efficacy and increase the risk of immune responses. Owing to these issues, specific regulatory guidance on biosimilars is continuously evolving, and there is some disagreement on which studies need to be implemented to approve a biosimilars. According to current literature, the following points on biosimilars deserve consideration: Biosimilars development is characterized by global harmonization, although several not fully answered questions remain regarding extrapolation of indications, switching or interchange ability, and tolerability; in patients with rheumatic diseases, the tolerability and efficacy of biosimilars in clinical practice remain to be established; several medical and patient associations have published position papers on biosimilars requesting that safety, efficacy, and traceability be carefully considered; long-term post marketing studies should be implemented to allow physicians to gain confidence in biosimilars.

    Related Conference of Biosimilars Approval to Biogenerics in Clinical Practice

    January 06-07, 2025

    29th Annual Meeting on Pharmaceutical Biotechnology

    London, UK
    February 24-25, 2025

    2nd International Conference on Pharmacognosy

    Madrid, Spain
    February 27-28, 2025

    8th International on Pharmacy and Pharmaceutical Conference

    Prague, Czech Republic
    March 10-11, 2025

    35th Annual European Pharma Congress

    Rome, Italy
    April 07-08, 2025

    4th International Conference and Expo on Pharmaceutics & Novel Drug Delivery Systems

    Vancouver, Canada
    April 14-15, 2025

    18th European Biosimilars Congress

    Paris, France
    April 24-25, 2025

    18th World Drug Delivery Summit

    London, UK
    May 05-06, 2025

    21st International Conference on Pharmaceutical Chemistry

    Rome, Italy
    May 05-06, 2025

    17th International Conference on Pharmaceutical Education and Practice

    Vancouver, Canada
    May 05-06, 2025

    19th World Drug Delivery Summit

    Vancouver, Canada
    May 19-20, 2025

    16th Annual Congress on Bioavailability and Bioequivalence

    Rome, Italy
    May 19-20, 2025

    7th International Conference and Exhibition on Pain Management

    Zurich, Switzerland
    June 02-03, 2025

    31st International Conference on Advanced Clinical Research and Clinical Trials

    Amsterdam, Netherlands
    June 10-11, 2025

    24th International Conference on Medicinal and Pharmaceutical Chemistry

    Vancouver, Canada
    June 10-11, 2025

    7th International Conference and Exhibition on Pharmaceutical Development and Technology

    Vancouver, Canada
    June 16-17, 2025

    18th International Conference and Exhibition on Pharmacovigilance & Drug Safety

    Frankfurt, Germany
    June 16-17, 2025

    3rd Global Online Summit on Nanoscience and Nanotechnology

    Zurich, Switzerland
    June 23-24, 2025

    25th World Congress on Pharmaceutical Sciences and Innovations in Pharma Industry

    Paris, France
    June 23-24, 2025

    27th International Congress on Pharmaceutical Biotechnology Research

    Paris, France
    June 23-24, 2025

    38th World Congress on Pharmacology

    Aix-en-Provence, France
    July 24-25, 2025

    5th World Congress on Cardiovascular Medicine Pharmacology

    Paris, France
    August 21-22, 2025

    5th International Conference on Pharmaceutical Chemistry

    Dublin, Ireland
    September 08-09, 2025

    26th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems

    Frankfurt, Germany
    September 23-24, 2025

    10th International Conference on Future Pharma and Innovations

    Amsterdam, Netherlands
    October 16-17, 2025

    18th International Conference on Pharmaceutics and Drug Safety

    Berlin, Germany
    October 22-23, 2025

    7th European Conference on Advance Clinical Trials and Research

    Paris, France
    November 27-28, 2025

    4th World Conference on Pharma Industry and Medical Devices

    Zurich, Switzerland
    November 27-28, 2025

    4th World Congress on Precision and Personalized Medicine

    Zurich, Switzerland

    Biosimilars Approval to Biogenerics in Clinical Practice Conference Speakers

      Recommended Sessions

      Related Journals

      Are you interested in